Link between obesity and Alzheimer's disease found
A recent study published by the Medical Journal Molecular Psychiatry, has stated that there is a very viable and possible link between obesity at age 50 or older and the development of Alzheimer’s disease.Even though Alzheimer’s disease is a condition that has been notoriously elusive to scientists, several medical breakthroughs and discoveries in recent times have placed us closer to understanding this condition, being able to prevent it and maybe finding a possible cure. In order to fully be able to reach better understanding of Alzheimer’s disease, getting to know the possible links to what can cause this condition.
According to the scientists from the National Institute on Aging (NIA) in the U.S., each unit added to the Body Mass Index in middle age means that the disease may appear 6.7 months before. Previous studies had already pointed out that some changes in lifestyle, such as an enhancement of the diet and regular exercise, could delay the manifestation of Alzheimer's disease.
The researchers in charge of this study have analyzed the data of 1,394 patients cognitively normal that underwent neuropsychological tests every two years for an average of fourteen years. Within that group, 142 people developed the disease and, between them, those with a higher body mass index at age 50 suffered the first symptoms of Alzheimer's disease earlier than the rest. Then, the researchers gathered data from 191 autopsies of people with Alzheimer’s disease, and based on their findings these scientists also found that obesity in middle age is associated with neurological damage in the brain related to Alzheimer's disease.
Madhay Thambisetty, principal author in this study stated that "These results are important because they add a significant amount of knowledge about the relationship between obesity and Alzheimer's disease, but on all indicate that maintaining a healthy BMI from middle age may contribute to a protective effect for the appearance of evil decades after".
For Thambisetty, further investigation is needed to involve a greater number of patients to determine the specific BMI, in which then an increase of the risk of an early manifestation of Alzheimer's disease. The authors of the study emphasize that the statistical results of this investigation will not delve into the mechanisms that make the overweight and obesity affect the emergence of the disease.
Although, more studies need to be performed this announcement has come to further unveil more of the nature of this disease that is affecting millions of people all around the world.